王先逸副教授

現職

• 國立陽明交通大學副教授

學歷

• 1991-1997 加拿大多倫多大學生理系博士
• 1985-1988 加拿大麥吉爾大學生物系碩士
• 1980-1984 東海大學生物系學士
  

經歷

• 國家衛生研究院助研究員

研究專長

• 電生理、動物行為、憂鬱症研究

發表論文

1. Chung-Wei Hsu and Sabrina Wang* (2021, Dec). Changes in the Orexin System in Rats Exhibiting Learned Helplessness Behaviors. Brain Sciences,11(12):1634. NSC 104-2320-B-010-012.
   
2. Yi-Fan Ma, Yi-An Lin, Chin-Lin Huang, Chih-Chieh Hsu, Sabrina Wang*, Shih‐Rung Yeh*, Ying-Chieh Tsai* (2021, Aug). Lactiplantibacillus plantarum PS128 ‐ Alleviates Exaggerated Cortical Beta Oscillations and Motor Deficits in the 6‐Hydroxydopamine Rat Model of Parkinson’s Disease. Probiotics and Antimicrobial Proteins, doi: 10.1007/s12602-021-09828-x.
   
3. Liao, J. F.; Cheng, Y. F.; You, S. T.; Kuo, W. C.; Huang, C. W.; Chiou, J. J.; Hsu, C. C.; Hsieh-Li, H. M.; Wang, S*.; Tsai, Y. C.*. Lactobacillus plantarum PS128 alleviates neurodegenerative progression in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced mouse models of Parkinson's disease. Brain Behav Immun. 2020; 90:26-46 (SCI).
4. Liu, T.Y., Kuo, P.H., Lu, M.L., Huang, M.C., Chen, C.H., Wu, T.H., Wang, S., Mao, W.C., Chen, H.C.. Quantifying the level of difficulty to treat major depressive disorder with antidepressants: Treatment Resistance to Antidepressants Evaluation Scale. PLoS One 2020; 15(1):e0227614 (SCI).
5. Chia-Li Wei, Sabrina Wang, Jui-Ting Yen, Yun-Fang Cheng, Chia-Li Liao, Chih-Chieh Hsu, Chien-Chen Wu d, and Ying-Chieh Tsai. Antidepressant-like activities of live and heat-killed Lactobacillus paracasei PS23 in chronic corticosterone-treated mice and possible mechanisms. Brain Research 2019; 1711:202-213 (SCI).
6. Liao, JF; Cheng, YF; Li, SW; Lee, WT; Hsu, CC; Wu, CC; Jeng, OJ; Wang, S; Tsai, YC. Lactobacillus plantarum PS128 ameliorates 2,5-Dimethoxy-4-iodoamphetamine-induced tic-like behaviors via its influences on the microbiota-gut-brain-axis. BRAIN RESEARCH BULLETIN 2019; 153:59-73 (SCI).
7. Cheng, L.H., Liu, Y.W., Wu, C.C., Wang, S., Tsai, Y.C.. Psychobiotics in mental health, neurodegenerative and neurodevelopmental disorders. JOURNAL OF FOOD AND DRUG ANALYSIS 2019; 27(3):632-648 (SCI).
8. Yen-Chin Wang, Hai-Ti Lin, Mong-Liang Lu, Ming-Chyi Huang, Chun-Hsin Chen, Tzu-Hua Wu, Sabrina Wang, Wei-Chung Mao, Po-Hsiu Kuo, Hsi-Chung Chen. The Association between the Sedative Loads and Clinical Severity Indicators in the First-onset Major Depressive Disorder . Frontiers in Psychiatry 2019; : (SCI).
9. Liao, T.-C., Lien, Y.-T., Wang, S., Huang, S.-L., Chan, C.-Y.. Comorbidity of Atopic Disorders with Autism Spectrum Disorder and Attention Deficit/Hyperactivity Disorder. JOURNAL OF PEDIATRICS 2016; 171:248-55. (SCI).
10. Wu, W.-C., Luh, D.-L., Chiang, Y.-C., Huang, C.-C., Wang, S., Wu, C.-C., Hurng, B.-S., Chang, Y.-H., Yen, L.-L., Chang, H.-Y.. Reciprocal relationship between unhealthy eating behaviours and depressive symptoms from childhood to adolescence: 10-year follow-up of the Child and Adolescent Behaviors in Long-Term Evolution study. Public Health Nutrition 2016; 19(9):1654-65 (SCI).
11. Liu, C.-P., Wu, T.-H., Lin, Y.-L.., Liu, C.-Y., Wang, S., Lin, S.-Y.. Tailoring Enzyme-Like Activities of Gold Nanoclusters by Polymeric Tertiary Amines for Protecting Neurons Against Oxidative Stress. Small 2016; 12(30):4127-35 (SCI).
12. Liu, W.-H., Chuang, H.-L., Huang, Y.-T., Wu, C-C., Chou, G.-T., Wang, S., and Tsai, Y.-C.. Alteration of behavior and monoamine levels attributable to Lactobacillus plantarum PS128 in germ –free mice. BEHAVIOURAL BRAIN RESEARCH 2016; 298:202-209 (SCI).
13. Liu, Y.-W., Liu, W.-H., Wu, C.-C., Juan, Y.-C., Wu, Y.-C., Tsai, H.-P., Wang, S., Tsai, Y.-C.. Psychotropic effects of Lactobacillus Plantarum PS128 in early life-stressed and naïve adult mice. BRAIN RESEARCH 2016; 1631:1-12 (SCI).
14. Mosa, AJ; Wang, S; Tan, YF; Wojtowicz, JM. Organotypic Slice Cultures for Studies of Postnatal Neurogenesis. Jove-Journal of Visualized Experiments 2015; 97(dio:10.3791/52353): (OI).
15. Fang, S.-Y., Wang, S., Huang, N., Yeh, H.-H., Chen, C.-Y.. Prenatal infection and autism spectrum disorders in childhood: A population-based case-control study in Taiwan. PAEDIATRIC AND PERINATAL EPIDEMIOLOGY 2015; 29(4):307-16 (SCI).
16. Lin, Y.-L. and Wang, S.. Prenatal LPS exposure increases depression-like behaviors and reduces hippocampal neurogenesis in adult rats. BEHAVIOURAL BRAIN RESEARCH 2014; 259:24-34 (SCI).
17. Lin, Y.-L., Lin, S.-Y., Wang, S.. Prenatal lipopolysaccharide exposure increases anxiety-like behaviors and enhances stress-induced corticosterone responses in adult rats. BRAIN BEHAVIOR AND IMMUNITY 2012; 26(3):459-468 (SCI).
18. Wu, H.H. and Wang, S.. Strain differences in the chronic mild stress animal model of depression. BEHAVIOURAL BRAIN RESEARCH 2010; 213(1):94-102 (SCI).
19. Ho, Y.-C. and Wang, S.. Adult neurogenesis is reduced in the dorsal hippocampus of rats displaying learned helplessness behavior. Neurosciences 2010; 171(1):153-61 (SCI).
20. Wang, S., Yan J.Y., Lo, Y.K., Carvey, P.M. and Ling, Z.. Dopaminergic and serotoninergic deficiencies in young adult rats prenatally exposed to the bacterial lipopolysaccharide. BRAIN RESEARCH 2009; 1265:196-204 (SCI).
21. Winocur, G., Wojtowicz, J.M., Sekeres, M., Snyder, J.S., Wang, S.. Inhibition of neurogenesis interferes with hippocampus-dependent memory function. Hippocampus 2006; 16(3):296-304 (SCI).
22. Wang, S., Kee, N., Preston, E. and Wojtowicz, J.M.. Electrophysiological correlates of neural plasticity compensating for ischemia-induced damage in the hippocampus. EXPERIMENTAL BRAIN RESEARCH 2005; 165(2):250-60. (SCI).

受邀演講

1. 2017/3/26 Animal studies of the potential of psychobiotics in the treatment of major depression 中華民國解剖學學會/第31界生物醫學聯合學術年會
2. 2013/3/23 The Potential Roles of Adult Neurogenesis and Maternal Infection in the Etiology of Major Depression中華民國解剖學學會/第28屆生物醫學聯合學術年會